The levels of specific globulins provide information about how well your immune system is working. This blood test measures the level of each type of protein in your blood, including the different types of globulins.

If protein levels are low, it can mean that you have liver or kidney disease. The two main types of blood proteins are globulins and albumin. This blood test measures the total amount of protein in your blood. There are different types of globulins called alpha, beta, and gamma globulins. Globulins play an important role in liver function, blood clotting, and fighting infection. They are made in your liver by your immune system. (2015).Globulins are a group of proteins in your blood.

Quantitative immunoglobulins: The test.

Understanding and interpreting serum protein electrophoresis. Clinical usefulness of the serum anion gap. Serum anion gap: Its uses and limitations in clinical medicine. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. A large increase in other positively charged ions, such as calcium and magnesium, can also lower the anion gap.

Increase in other positively charged ions.

In high concentrations, it can lower the anion gap. Lithium is positively charged and is sometimes prescribed for treatment of bipolar disorder. This affects the calculation of the anion gap and gives a falsely low anion gap result. Although negatively charged, bromide can interfere with the calculation of chloride. High concentrations of bromide can lead to neurologic or dermatologic symptoms. Bromide is present in some sedative drugs, medication for myasthenia gravis, and some herbal medications. There are a few more rare causes of low anion gap. They may also order a serum or urine protein electrophoresis test to help monitor and diagnose your condition. Your doctor may order a blood test to assess the levels of immunoglobulins in your blood. Polyclonal gammopathies are often associated with various inflammatory diseases. Monoclonal gammopathies can be associated with conditions such as multiple myeloma. Overproduction of IgG can sometimes lead to a low anion gap value. There are many types of immunoglobulins, but one type, called IgG, is positively charged. Immunoglobulins, also known as antibodies, play a critical role in your immune system. This condition refers to an overabundance of proteins (immunoglobulins) in your blood.

Lower-than-normal albumin can be caused by the following conditions: If your doctor suspects hypoalbuminemia, they may order a blood test to assess the albumin levels in your blood. Albumin is one of the most abundant proteins in circulation, so a drop in the level of this protein would affect the anion gap. Hypoalbuminemia means that there are low levels of a protein (albumin) in your blood. Within this small percentage, over 90 percent of the results were due to laboratory error in calculating one of the electrolyte values. A published review found that out of 67,000 calculations of anion gap, a low anion gap was calculated less than 1 percent of the time. If your test indicates a low anion gap value, your doctor may order a second test to account for laboratory error.īecause the anion gap is calculated from the results of the electrolyte panel, accurate measurement of the individual electrolytes is necessary. The most common causes of low anion gap results may include the following. Having a low anion gap value is very rare. Potential causes and diagnosis of a low anion gap

Low ag ratio blood test